Healthcare utilization and costs in patients with rheumatoid arthritis using biologics or tofacitinib: a nationwide, population-based study - Summary - MDSpire

Healthcare utilization and costs in patients with rheumatoid arthritis using biologics or tofacitinib: a nationwide, population-based study

  • By

  • Yen-Ju Chen

  • Wei-Li Ho

  • Hsian-Min Chen

  • Yi-Ming Chen

  • Hsin-Hua Chen

  • June 22, 2026

  • 0 min

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Objective:

To investigate healthcare utilization and costs in rheumatoid arthritis (RA) patients pre- to post-initiation of biologic agents in Taiwan from 1996 to 2017.

Approach:
    Key Findings:
    • RA patients have higher medical expenditures compared to non-RA patients.
    • The introduction of biologics has led to increased drug costs but decreased overall healthcare costs due to fewer emergency visits and hospitalizations.
    • Previous studies focused mainly on TNF inhibitors, with limited data on other biologics and tofacitinib.
    Interpretation:

    The study provides insights into healthcare resource utilization and costs associated with various biologic treatments for RA in Taiwan.

    Limitations:
    • Exclusion of patients treated with Rituximab, limiting the generalizability of findings.
    • Focus on a single-payer system may not reflect costs in other healthcare settings, potentially affecting the applicability of the results.
    Conclusion:

    The study provides a detailed analysis of healthcare utilization and costs associated with different biologic treatments for RA.

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