Hair cortisol as psychotherapy process parameter – an inpatient pediatric psychosomatic study - Summary - MDSpire

Hair cortisol as psychotherapy process parameter – an inpatient pediatric psychosomatic study

  • By

  • Tim Botschek

  • Anna Röhlich

  • Burkhard Brosig

  • July 7, 2026

  • 0 min

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Objective:

To evaluate the efficacy and sustainability of inpatient psychosomatic therapy in children and adolescents by examining both psychological outcomes and biological markers.

Approach:
  • Participants: 58 patients were assessed at seven time points before, during, and after treatment.
  • Measurements: Hair cortisol concentration (HCC) was measured as a neuroendocrine parameter of long-term stress regulation, alongside psychometric data collected using five validated questionnaires.
Key Findings:
  • Significant improvements were observed in perceived stress, depressive and anxiety symptoms, family functioning, and internalizing symptoms during inpatient treatment.
  • These effects remained stable at three- and six-month follow-ups, although there were transient increases in depressive symptoms and family problems.
  • Hair cortisol concentration (HCC) showed a significant decrease from admission to discharge and remained stable across follow-ups.
Interpretation:

The results support the efficacy of inpatient pediatric psychosomatic interventions on both psychological outcomes and neuroendocrine stress regulation.

Limitations:
  • The study's design may not fully capture the complexity of psychosomatic disorders, potentially limiting the generalizability of the findings.
  • Existing literature on pediatric psychosomatic therapy is limited and lacks comprehensive follow-up data, which may affect the understanding of long-term treatment effects.
Conclusion:

The study highlights the value of integrating biological markers into psychotherapy research.

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