Developmental outcomes of young children with an autism diagnosis and its associated clinical correlates - Summary - MDSpire

Developmental outcomes of young children with an autism diagnosis and its associated clinical correlates

  • By

  • Ramkumar Aishworiya

  • Erdembileg Sundarimaa

  • Siew-Pang Chan

  • Rakhi Vashishtha

  • June 15, 2026

  • 0 min

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Objective:

To identify the developmental trajectory of young children with an autism diagnosis and clinical factors associated with better developmental outcomes, including specific characteristics such as age at diagnosis and baseline T-scores.

Approach:
    Key Findings:
    • Improvements in Receptive Language (mean T-score increased from 26.5 to 32.0, p=0.003) and Expressive Language (mean T-score increased from 26.0 to 30.7, p=0.010) were observed.
    • Higher baseline T-scores were associated with better follow-up scores across multiple developmental domains, including Fine Motor and Early Learning Composite.
    • Age at initial presentation was significantly associated with Fine Motor outcomes (β = 1.26, p=0.031).
    • Intervention hours were not independently associated with developmental outcomes in the full sample, but higher hours correlated with better outcomes in children with baseline developmental delay.
    Interpretation:

    Child-level characteristics, such as age at diagnosis and baseline T-scores, significantly influence developmental trajectories beyond intervention hours alone.

    Limitations:
    • The study is based on a small sample size of 38 children, which may limit the generalizability of the findings.
    • Findings may not generalize to all children diagnosed with autism due to the specific setting and sample characteristics, including potential biases in intervention access.
    Conclusion:

    Early identification and intervention for autism are supported, but individual characteristics, such as age at diagnosis and baseline developmental status, play a significant role in shaping developmental outcomes.

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