To provide the strategic application of differentially processed adipose products by matching material properties to anatomical requirements for effective facial rejuvenation.
Key Findings:
All patients achieved significant aesthetic improvement with no major complications.
Early side effects resolved spontaneously within 3 weeks.
Sixteen patients required secondary procedures due to partial volume absorption.
SVF-gel was effective in periorbital rejuvenation and skin quality enhancement.
HDF and AMC provided stable structural support in deeper facial regions.
Patient satisfaction scores improved from 5.26 ± 1.84 preoperatively to 8.01 ± 1.09 postoperatively.
Observer assessments using the Global Aesthetic Improvement Scale (GAIS) yielded a postoperative score of 1.88 ± 0.65.
Interpretation:
The targeted application of processed adipose products based on their biological properties and recipient site requirements enables effective, multilayer facial restoration, addressing both volumetric deficits and skin quality concerns, with significant implications for clinical practice.
Limitations:
Retrospective design may introduce selection bias.
Limited follow-up duration for assessing long-term outcomes may affect the reliability of findings.
Sample size may not be representative of broader populations.
Conclusion:
The study supports the use of multilayered adipose grafting tailored to anatomical needs as a comprehensive solution for facial rejuvenation, emphasizing the importance of personalized approaches in clinical settings.
