Effectiveness of Manuka Honey Eye Drops for Alleviating Dry Eye Symptoms Post-Cataract Surgery: A Prospective Controlled Trial - Summary - MDSpire

Effectiveness of Manuka Honey Eye Drops for Alleviating Dry Eye Symptoms Post-Cataract Surgery: A Prospective Controlled Trial

  • By

  • Javier García-Bardera

  • Javier García-Bella

  • Fiorella K. Cuba-Sulluchuco

  • Bárbara Burgos-Blasco

  • Pedro Arriola-Villalobos

  • Jose Manuel Benítez-Del-Castillo

  • April 28, 2026

  • 0 min

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Objective:

To evaluate the efficacy of Manuka honey eye drops in improving dry eye symptoms and reducing ocular inflammation after cataract surgery, specifically compared to sodium hyaluronate eye drops.

Key Findings:
  • At 1 month, the Manuka group showed a greater reduction in OSDI score compared to the control group (-27.3 vs -4.3, p = 0.007).
  • Conjunctival redness was lower in the Manuka group at 1 month (adjusted mean difference: -0.56, p = 0.014).
  • No significant differences were observed in NIBUT between groups.
Interpretation:

Manuka honey eye drops were associated with greater improvement in postoperative dry eye symptoms and reduced ocular surface inflammation compared to sodium hyaluronate, but results should be interpreted with caution due to study limitations.

Limitations:
  • The study was non-randomized, which may introduce selection bias and affect the reliability of the findings.
  • The sample size was relatively small, potentially limiting the generalizability of the findings.
Conclusion:

Manuka honey eye drops may be a beneficial treatment for alleviating dry eye symptoms post-cataract surgery, but findings should be interpreted with caution and further research is needed to validate these results.

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