Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster - Summary - MDSpire

Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster

  • By

  • Folasade P. May

  • Suzanne Brodney

  • Jessica J. Tuan

  • Sapna Syngal

  • Andrew T. Chan

  • Beth Glenn

  • Gina Johnson

  • Yuchiao Chang

  • David A. Drew

  • Beverly Moy

  • Nicolette J. Rodriguez

  • Erica T. Warner

  • Adjoa Anyane-Yeboa

  • Chinedu Ukaegbu

  • Anjelica Q. Davis

  • Kimberly Schoolcraft

  • Susan Regan

  • Kelley Le Beaux

  • Ellen T. Lee

  • Roopa Bhat

  • Alexis Gordon

  • Linh K. Phan

  • Andrea Fernanda Cortés Chirino

  • Caylin J. Marotta

  • Rachel G. Z. Kindermann

  • Jennifer S. Haas

  • June 1, 2026

  • 0 min

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Objective:

To compare the effectiveness of mailed FIT outreach with automated text reminders against mailed FIT-DNA with a manufacturer’s patient assistance program in increasing colorectal cancer screening uptake in community health clinics.

Key Findings:
  • Patients who received mailed FIT outreach had a significantly higher screening completion rate (30.0%) compared to those who did not (9.7%), highlighting the effectiveness of outreach strategies.
  • The FIT-DNA test is gaining popularity due to its higher sensitivity and manufacturer support, which may enhance screening rates.
Interpretation:

The study suggests that mailed outreach strategies can effectively increase CRC screening rates in community health clinics, particularly among underserved populations, and may inform future public health initiatives.

Limitations:
  • The study did not blind participants or sites to the allocation, which may introduce bias in reporting and participation.
  • The follow-up care for patients with abnormal results varied by location, potentially affecting overall screening outcomes.
Conclusion:

The findings indicate potential for improved CRC screening participation through targeted mailed outreach strategies.

Original Source(s)

Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster

  • by Folasade P. May, Suzanne Brodney, Jessica J. Tuan, Sapna Syngal, Andrew T. Chan, Beth Glenn, Gina Johnson, Yuchiao Chang, David A. Drew, Beverly Moy, Nicolette J. Rodriguez, Erica T. Warner, Adjoa Anyane-Yeboa, Chinedu Ukaegbu, Anjelica Q. Davis, Kimberly Schoolcraft, Susan Regan, Kelley Le Beaux, Ellen T. Lee, Roopa Bhat, Alexis Gordon, Linh K. Phan, Andrea Fernanda Cortés Chirino, Caylin J. Marotta, Rachel G. Z. Kindermann, Jennifer S. Haas

  • June 1, 2026

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