To record the actual in-hospital incidence of VTE at the federal level from 2020 to 2024 and characterize VTE regarding anatomic region, risk factors, inpatient treatment, occurrence of PE, and in-hospital mortality.
Key Findings:
VTE is rare in children, with incidences of 1.4 to 4.9 in 100,000 children per year, highlighting the need for awareness in clinical settings.
Neonates show a higher occurrence of VTE compared to older children, with a second peak during late adolescence, indicating age-specific risk factors.
Common risk factors include genetic disorders, malignancies, organ dysfunction, and modifiable factors like obesity and immobility, which should be targeted in prevention strategies.
Interpretation:
The study highlights the complexity of VTE management in pediatric patients due to a lack of standardized care and reliance on adult studies for treatment guidelines, emphasizing the need for tailored approaches.
Limitations:
The study relies on a national database, which may not capture all cases or nuances of VTE in pediatric patients, such as specific clinical presentations.
There is a lack of original research and registries specifically for pediatric VTE, leading to weak recommendations and highlighting the need for further studies.
Conclusion:
There are no uniform standards of care for VTE and PE management in children and adolescents, necessitating careful therapeutic decisions and the development of standardized protocols.
