Images in Vascular Medicine: When coronary anatomy goes the wrong way—A diagnostic challenge - Summary - MDSpire

Images in Vascular Medicine: When coronary anatomy goes the wrong way—A diagnostic challenge

  • By

  • Carla Oliveira Ferreira

  • Mónica Dias

  • Francisco Fernandes

  • João Costa

  • Cátia Costa Oliveira

  • June 23, 2026

  • 0 min

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Objective:

To present a case of anomalous origin of the left anterior descending artery from the pulmonary artery (ALADAPA) and highlight the importance of multimodality imaging in diagnosis.

Approach:
  • Case Presentation: A 59-year-old woman with progressive dyspnea underwent echocardiography, coronary angiography, and CT angiography, revealing ectatic coronary arteries and ALADAPA.
  • Diagnostic Imaging: Transthoracic echocardiography showed left ventricle dilation and diastolic flow signals. Coronary angiography confirmed the anomalous artery origin, and CT angiography supported these findings.
  • Functional Assessment: Myocardial perfusion scintigraphy indicated moderate-to-severe reversible ischemia in the anterior myocardial territory.
  • Surgical Intervention: The patient was referred for surgical correction to restore antegrade perfusion.
Key Findings:
  • ALADAPA is exceptionally rare, with only 52 reported cases.
  • The condition may remain undetected until adulthood due to collateral development.
  • Multimodality imaging is crucial for early recognition and diagnosis.
Interpretation:

Surgical reimplantation of the anomalous artery into the aorta is a treatment option to address complications such as myocardial ischemia and sudden cardiac death.

Limitations:
  • The rarity of ALADAPA may limit the generalizability of findings to broader populations.
  • Only a few cases have been documented in the literature, which may affect the understanding of the condition.
Conclusion:

Recognizing ALADAPA early and considering surgical intervention may help manage the condition and reduce the risk of serious cardiac events.

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