Brucellosis associated with acute kidney injury and pancytopenia: a case report and review of the literature - Summary - MDSpire

Brucellosis associated with acute kidney injury and pancytopenia: a case report and review of the literature

  • By

  • Ya Wang

  • Fangqiu Yu

  • Wei Wang

  • June 12, 2026

  • 0 min

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Objective:

To report a rare case of brucellosis presenting with acute kidney injury and haemophagocytic syndrome, a condition characterized by excessive activation of the immune system.

Key Findings:
  • The patient presented with unexplained fever, progressive pancytopenia, and elevated serum creatinine.
  • Blood culture confirmed the presence of Brucella.
  • Imaging showed increased renal cortical echogenicity, indicating renal involvement.
Interpretation:

The case emphasizes the importance of considering rare pathogens like Brucella in patients with unexplained fever and clinical features that deviate from typical presentations.

Limitations:
  • The case is based on a single patient, limiting generalizability to broader populations.
  • Diagnostic challenges may lead to underreporting of brucellosis cases, affecting the understanding of its prevalence.
Conclusion:

The patient showed significant improvement following appropriate treatment, highlighting the need for awareness of rare complications associated with brucellosis to enhance early diagnosis and management.

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