Assessment of Sexual Dysfunction Rates and Associated Factors in Cancer Patients: A Systematic Review and Meta-Analysis - Summary - MDSpire

Assessment of Sexual Dysfunction Rates and Associated Factors in Cancer Patients: A Systematic Review and Meta-Analysis

  • By

  • Amirmohammad Dahouri

  • Mina Hosseinzadeh

  • Mohammad Hasan Sahebihagh

  • January 28, 2026

  • 0 min

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Objective:

To comprehensively examine the prevalence of sexual dysfunction (SD) across diverse cancer types and identify modifiable and non-modifiable determinants, highlighting their significance for patient care.

Key Findings:
  • Sexual dysfunction affects a significant proportion of cancer patients, with prevalence rates ranging from 53% to 91% depending on cancer type, including prostate and breast cancers.
  • Barriers to addressing SD include patient reluctance to discuss sexual issues and healthcare providers' lack of training.
  • Existing literature on SD in cancer survivors is fragmented, leading to inconsistent estimates of prevalence and risk factors.
Interpretation:

The findings highlight the critical need for improved recognition and management of sexual dysfunction in cancer care, emphasizing its importance for overall quality of life and patient satisfaction.

Limitations:
  • Variability in study design and assessment tools across included studies may affect the reliability of prevalence estimates.
  • Limited focus on moderators such as treatment modality and time since treatment in existing literature, as well as potential biases in study selection.
Conclusion:

Addressing sexual dysfunction is essential for holistic, patient-centered cancer care, necessitating further research and clinical attention, particularly in developing targeted interventions.

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