To evaluate and compare the accuracy of deterministic versus probabilistic tractography in mapping the corticospinal tract (CST) during brain tumor resections.
Key Findings:
Probabilistic tractography showed a mean distance of 12.01 ± 8.92 mm, while deterministic tractography showed 27.71 ± 17.14 mm.
The mean difference between DES threshold and probabilistic tractography was not significant (p=0.24), while it was significant for deterministic tractography (p<0.001).
Probabilistic tractography had lower RMSE against the gold standard compared to deterministic (10.1 vs 25.7).
Interpretation:
Probabilistic tractography provides a more accurate representation of the CST compared to deterministic methods, enhancing surgical safety during tumor resections.
Limitations:
Single-center study may limit generalizability.
Retrospective design may introduce selection bias.
Conclusion:
Integrating probabilistic tractography with direct electrical stimulation enhances surgical safety and optimizes tumor resection while minimizing postoperative motor deficits.
