Case Report: Catheter-associated multidrug-resistant Leclercia adecarboxylata bloodstream infection in a colon tumor patient - Summary - MDSpire

Case Report: Catheter-associated multidrug-resistant Leclercia adecarboxylata bloodstream infection in a colon tumor patient

  • By

  • Ning Du

  • Dan You

  • Zhe Chen

  • June 18, 2026

  • 0 min

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Objective:

To report a case of catheter-associated bloodstream infection caused by multidrug-resistant L. adecarboxylata in a colon tumor patient, highlighting its clinical significance.

Key Findings:
  • L. adecarboxylata was isolated from both peripheral blood and the central venous catheter, indicating a serious infection risk.
  • The patient was treated successfully with meropenem after initial cefoperazone-sulbactam failure, underscoring the importance of appropriate antibiotic selection.
  • Multidrug-resistant strains of L. adecarboxylata can occur, particularly in immunocompromised patients, necessitating vigilance in treatment.
Interpretation:

The case highlights the potential for multidrug-resistant L. adecarboxylata to cause serious infections in patients with risk factors such as malignancy and catheter use, suggesting a need for updated treatment guidelines.

Limitations:
  • This is a single case study, limiting generalizability and potential biases in case reporting.
  • Lack of extensive antimicrobial susceptibility data for L. adecarboxylata may hinder understanding of resistance patterns.
Conclusion:

Treatment of L. adecarboxylata infections should be guided by antimicrobial sensitivity tests, with an emphasis on ongoing surveillance of resistance patterns.

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