Development and Internal Validation of a Perioperative Nomogram for Predicting Postoperative Delirium in Geriatric Patients with Intertrochanteric Fractures Undergoing Internal Fixation with Preoperative Low-Dose Dexamethasone - Summary - MDSpire

Development and Internal Validation of a Perioperative Nomogram for Predicting Postoperative Delirium in Geriatric Patients with Intertrochanteric Fractures Undergoing Internal Fixation with Preoperative Low-Dose Dexamethasone

  • By

  • Liu, Wanshun

  • Lu, Yunxi

  • Chen, Jun

  • Lv, Yuanhao

  • Wa, Qingde

  • May 25, 2026

  • 0 min

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Objective:

To develop and internally validate a nomogram specifically for predicting postoperative delirium (POD) in elderly patients undergoing internal fixation for intertrochanteric fractures, all of whom received a standardized preoperative low-dose intravenous dexamethasone.

Approach:
    Key Findings:
    • Incidence of POD was 12.5% (31/248).
    • Three independent predictors identified: age (OR = 1.102), preoperative monocyte count (OR = 7.566), and postoperative transfer to ICU (OR = 2.923).
    • Nomogram demonstrated good discriminative ability with an AUC of 0.803, accuracy of 0.843, sensitivity of 0.821, and specificity of 0.847.
    Interpretation:

    The nomogram may facilitate early identification of high-risk individuals within this patient subset and support targeted preventive strategies immediately following surgery.

    Conclusion:

    This model is the first perioperative nomogram incorporating three perioperative variables to predict POD in geriatric intertrochanteric fracture patients undergoing a standardized preoperative dexamethasone regimen.

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