To describe a case of long-term hypoparathyroidism following SARS-CoV-2 infection and review existing literature on COVID-19-associated hypoparathyroidism.
Key Findings:
The patient exhibited persistently low PTH levels and hyperphosphatemia, consistent with permanent hypoparathyroidism.
Coexistent Hashimoto’s thyroiditis was identified, suggesting a potential autoimmune contribution.
Young patients without prior neck surgery and with severe hypocalcemia not correlating with infection severity may have a higher likelihood of persistent hypoparathyroidism.
Interpretation:
The findings suggest that SARS-CoV-2 infection may contribute to new-onset hypoparathyroidism or exacerbate existing conditions, warranting extended follow-up and comprehensive evaluation.
Limitations:
Lack of baseline calcium/PTH data prior to infection.
Limited number of case reports and lack of systematic follow-up in existing literature.
Conclusion:
This case highlights the need for further investigation into the long-term effects of COVID-19 on parathyroid function and the potential autoimmune mechanisms involved.
