Prehabilitation Prior to Colorectal Cancer Surgery: Impact and Implementation - Summary - MDSpire
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Enhancing Outcomes Through Preoperative Rehabilitation for Colorectal Cancer Surgery: Strategies and Effects

  • By

  • Elize W. Lockhorst

  • Theresia A. M. Backhuijs

  • Teun M. E. Kerkhoff

  • Robert R. J. Coebergh van den Braak

  • Ninos Ayez

  • Cornelis Verhoef

  • Paul D. Gobardhan

  • Jennifer M. J. Schreinemakers

  • June 18, 2026

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Objective:

To evaluate the implementation of a standardised prehabilitation programme for patients undergoing elective colorectal cancer surgery and assess its effects and challenges.

Approach:
  • Prehabilitation Programme: The standardised prehabilitation programme includes exercise, nutritional guidance, and psychological support, focusing on enhancing patient participation and improving postoperative outcomes.
Key Findings:
  • Up to 44% of patients undergoing major abdominal oncological surgery experience postoperative complications.
  • Higher levels of physical activity and lower inactivity are positive predictors for postoperative functional recovery.
  • Reduced cardiorespiratory fitness prior to surgery is associated with increased risk of postoperative complications and mortality.
  • Frailty correlates with higher rates of postoperative complications, mortality, readmission, reoperation, and length of stay.
Interpretation:

Limitations:
  • Limited literature on the pitfalls and challenges of implementing prehabilitation programmes.
  • Insufficient knowledge regarding patient participation in prehabilitation.
Conclusion:

The study emphasizes the significance of a standardised prehabilitation programme in enhancing surgical outcomes for patients with colorectal cancer.

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