Examining the Link Between a Modified Cardiometabolic Index and Cardiovascular Disease Risk in Adults with Early Cardiovascular-Kidney-Metabolic Syndrome: Findings from a Prospective Cohort Study - Summary - MDSpire

Examining the Link Between a Modified Cardiometabolic Index and Cardiovascular Disease Risk in Adults with Early Cardiovascular-Kidney-Metabolic Syndrome: Findings from a Prospective Cohort Study

  • By

  • Hongcai Wang

  • Kaixuan Li

  • Chang Sheng

  • Xin Ye

  • Guoqiang Lin

  • March 13, 2026

  • 0 min

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Objective:

To investigate the association between the Modified Cardiometabolic Index (MCMI) and the incidence risk of cardiovascular diseases in adults with Cardiovascular-Kidney-Metabolic (CKM) syndrome stages 0–3, highlighting the importance of early detection.

Key Findings:
  • MCMI is significantly associated with increased risk of cardiovascular disease in CKM syndrome stages 0–3, with higher MCMI scores correlating to a XX% increase in incidence of heart disease and stroke.
Interpretation:

The findings suggest that MCMI may serve as a useful tool for identifying individuals at higher risk of cardiovascular events within the CKM population.

Limitations:
  • The study relies on self-reported data for CVD diagnosis, which may introduce reporting bias.
  • The cross-sectional nature of the data limits causal inferences.
  • Findings may not be generalizable to populations outside of China.
Conclusion:

MCMI is a promising index for assessing cardiovascular risk in adults with early CKM syndrome, underscoring the need for targeted prevention strategies in clinical practice.

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