Utilizing Optical Coherence Tomography Angiography and Optical Coherence Tomography for the Prediction of Polyvascular Disease - Summary - MDSpire

Utilizing Optical Coherence Tomography Angiography and Optical Coherence Tomography for the Prediction of Polyvascular Disease

  • By

  • Minghao Liu

  • Shiqi Ouyang

  • Bowen Zhang

  • Shuangtong Shao

  • Pan Fan

  • Tianyu Wu

  • Huahui Ren

  • Qianhui Sun

  • Dirui Zhang

  • Ning Wang

  • Chen Zhao

  • Shengliang Liu

  • Xia Gu

  • Yunling Li

  • Xinxin Zhu

  • Xing Luo

  • Shan Zhang

  • Sining Hu

  • Gary S. Mintz

  • Bo Yu

  • Haibo Jia

  • February 27, 2026

  • 0 min

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Objective:

To investigate retinal microvascular alterations and coronary plaque features in ACS patients with and without polyvascular disease (PVD), highlighting the importance of these findings for early diagnosis.

Key Findings:
  • Distinct retinal microvascular changes observed in ACS patients with PVD, indicating potential early diagnostic markers.
  • High-risk coronary plaque features identified in patients with PVD, suggesting a need for targeted interventions.
  • Microvascular dysfunction may serve as an early marker for PVD, warranting further exploration.
Interpretation:

Retinal imaging via OCTA may provide insights into systemic endothelial health and help predict PVD in ACS patients, potentially guiding clinical management.

Limitations:
  • Single-center study may limit generalizability.
  • Equipment lease termination affected sample size for OCTA imaging.
  • Retrospective design may introduce selection bias, affecting the reliability of findings.
Conclusion:

OCTA and OCT may be valuable tools for early detection of PVD in ACS patients, warranting further investigation into their clinical applications.

Original Source(s)

Utilizing Optical Coherence Tomography Angiography and Optical Coherence Tomography for the Prediction of Polyvascular Disease

  • by Minghao Liu, Shiqi Ouyang, Bowen Zhang, Shuangtong Shao, Pan Fan, Tianyu Wu, Huahui Ren, Qianhui Sun, Dirui Zhang, Ning Wang, Chen Zhao, Shengliang Liu, Xia Gu, Yunling Li, Xinxin Zhu, Xing Luo, Shan Zhang, Sining Hu, Gary S. Mintz, Bo Yu, Haibo Jia

  • February 27, 2026

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