Digital phenotyping of affect and stress in emerging adults - Summary - MDSpire

Digital phenotyping of affect and stress in emerging adults

  • By

  • Coralie S. Phanord

  • Luka L. Ruzic

  • Siddharth Kalyanasundaram

  • Sofia Barnes-Horowitz

  • Naomi P. Friedman

  • Theodora Chaspari

  • Roselinde H. Kaiser

  • June 4, 2026

  • 0 min

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Objective:

To model smartphone sensor-based behavioral markers to predict affect and stress over a one-year period in emerging adults, addressing significant gaps in existing research and comparing different modeling approaches.

Key Findings:
  • Model 1 Group General identified behaviors predicting daily affect/stress across individuals but lacked generalizability, highlighting the need for more robust models.
  • Models 2 and 3 outperformed Model 1, with Model 2 offering the best balance of accuracy and stability, suggesting a promising direction for future research.
  • Participant ID was a significant contributor to Model 2's predictive power, indicating stable individual differences that could inform personalized interventions.
  • Model 3 revealed person-specific behavior patterns predicting daily affect, but had limited reliability, indicating a need for further refinement.
Interpretation:

The study highlights the complementary strengths and weaknesses of different machine learning models for predicting affect and stress from behavioral features, contributing valuable insights to the field.

Limitations:
  • The sample size was small (n = 24), which may limit generalizability; future studies should aim for larger, more diverse samples.
  • Model reliability for person-specific predictions was limited, suggesting the need for improved methodologies in future research.
Conclusion:

Future research should rigorously compare personalized and hybrid modeling strategies for predicting affective and stress outcomes, emphasizing the practical applications of these findings in mental health interventions.

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