Single-center experience of interventional therapy for congenital portal-systemic shunt in children - Summary - MDSpire

Single-center experience of interventional therapy for congenital portal-systemic shunt in children

  • By

  • Xiangfeng Guo

  • Qi Di

  • Gang Shen

  • July 1, 2026

  • 0 min

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Objective:

To investigate the safety and short-term efficacy of interventional therapy for congenital portosystemic shunt (CPSS) in children.

Approach:
  • Study Design: A retrospective analysis of clinical data from 26 children with CPSS who underwent interventional therapy at Capital Center for Children's Health.
  • Patient Categorization: Patients were categorized into intrahepatic portal-systemic shunt group (18 cases) and Abernethy malformation group (8 cases).
  • Interventional Techniques: Techniques included coil embolization and Amplatzer occluder embolization.
  • Follow-Up: Postoperative follow-up was conducted for 1–12 months to evaluate success rates, complications, and improvements in liver function.
Key Findings:
  • Success rate of interventional therapy was 73% (19/26).
  • Technical success rate was 94.4% in the intrahepatic portal-systemic shunt group and 25% in the Abernethy malformation group.
  • Mild complications occurred in 3.8% of cases, with no severe complications reported.
  • Postoperative normalization of liver function parameters was achieved in 63% of patients, with 100% improvement in blood ammonia levels.
Interpretation:

Limitations:
  • Small sample size of 26 patients.
  • Retrospective study design may introduce bias.
Conclusion:

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