To investigate the safety and short-term efficacy of interventional therapy for congenital portosystemic shunt (CPSS) in children.
Approach:
Study Design: A retrospective analysis of clinical data from 26 children with CPSS who underwent interventional therapy at Capital Center for Children's Health.
Patient Categorization: Patients were categorized into intrahepatic portal-systemic shunt group (18 cases) and Abernethy malformation group (8 cases).
Interventional Techniques: Techniques included coil embolization and Amplatzer occluder embolization.
Follow-Up: Postoperative follow-up was conducted for 1–12 months to evaluate success rates, complications, and improvements in liver function.
Key Findings:
Success rate of interventional therapy was 73% (19/26).
Technical success rate was 94.4% in the intrahepatic portal-systemic shunt group and 25% in the Abernethy malformation group.
Mild complications occurred in 3.8% of cases, with no severe complications reported.
Postoperative normalization of liver function parameters was achieved in 63% of patients, with 100% improvement in blood ammonia levels.