Blood urea nitrogen to albumin ratio and 1-year mortality after hip fracture surgery in older adults: a retrospective cohort study - Summary - MDSpire

Association of Blood Urea Nitrogen to Albumin Ratio with One-Year Mortality Following Hip Fracture Surgery in Elderly Patients: A Retrospective Cohort Analysis

  • By

  • Jian Wang

  • Liuyang Shi

  • Zihan Zhang

  • Jiale Guo

  • Junjie Xu

  • July 17, 2026

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Objective:

To evaluate the association between blood urea nitrogen to albumin ratio (BAR) and the risk of 1-year all-cause mortality after hip fracture (HF) surgery in elderly patients.

Approach:
  • Study Design: A single center, retrospective cohort study including patients aged 60 years or older who underwent surgery for HF between May 2016 and December 2021.
  • Data Collection: Clinical data and laboratory test results were obtained from electronic medical records, and survival status was confirmed through follow-up.
  • Statistical Analysis: Logistic regression analysis was used to evaluate associations between BAR and 1-year mortality, with further analyses including RCS, AUC, sensitivity, and subgroup analyses.
Key Findings:
  • A total of 521 patients were included, of whom 77 died within 1 year after hip fracture, corresponding to a mortality rate of 14.8%.
  • In univariate analysis, several indicators including BAR were associated with mortality risk.
  • After adjustments, only BAR remained significantly associated with mortality (OR = 1.13, 95% CI: 1.05–1.22, P < 0.01).
  • The AUC for BAR was 0.67, indicating moderate predictive performance.
Interpretation:

Higher BAR early after admission is associated with increased risk of 1-year mortality in older patients with hip fracture.

Limitations:
  • The study is retrospective and conducted at a single center, which may limit generalizability.
  • The predictive performance of BAR was moderate and requires further validation in multicenter prospective studies.
Conclusion:

BAR may serve as a simple and low-cost auxiliary indicator for risk stratification in older patients after hip fracture surgery.

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