Objective:

To identify the risk factors for acute kidney injury (AKI) requiring dialysis following endoscopic retrograde cholangiopancreatography (ERCP) in patients with liver cirrhosis.

Approach:

• Study Design: Retrospective analysis using data from the US Nationwide Inpatient Sample (NIS) database.
• Patient Selection: Included patients aged ≥20 years with liver cirrhosis who underwent ERCP from 2016 to 2020.
• Outcome Definition: Primary outcome was dialysis-requiring AKI identified through ICD-10 diagnostic and procedure codes.
• Statistical Analysis: Used univariate and multivariable logistic regression to assess associations between variables and AKI.

Key Findings:

• Patients with liver cirrhosis have a significant incidence of AKI post-ERCP.
• Specific risk factors associated with dialysis-requiring AKI were identified.

Interpretation:

Limitations:

• Data was limited to ICD-10 codes, lacking laboratory data for AKI definition.
• The study was retrospective and may be subject to biases inherent in such designs.

Conclusion:

Identifying risk factors for AKI in patients with liver cirrhosis undergoing ERCP is important.