To report a case of childhood-onset systemic lupus erythematosus (cSLE) presenting with growth retardation and delayed puberty, highlighting the significance of atypical presentations.
Key Findings:
cSLE can present atypically with growth retardation and delayed puberty, as seen in this case.
Initial symptoms may include proteinuria and immunological abnormalities, which are critical for diagnosis.
Despite treatment, growth and pubertal development may not fully normalize, indicating the need for ongoing management.
Interpretation:
cSLE should be considered in adolescents with unexplained short stature or pubertal delay, especially with accompanying proteinuria or immunological issues, to facilitate timely intervention.
Limitations:
The case is based on a single patient, limiting generalizability and potential biases in case reporting.
Long-term outcomes and the impact of treatment on growth and puberty require further study to establish broader applicability.
Conclusion:
Early recognition and multidisciplinary management of cSLE are crucial for improving long-term growth and clinical outcomes, emphasizing the need for awareness among healthcare providers.
