Undetected Anal and Anorectal Tumors in Endoscopic Assessments: A Retrospective Analysis Over Ten Years - Summary - MDSpire

Undetected Anal and Anorectal Tumors in Endoscopic Assessments: A Retrospective Analysis Over Ten Years

  • By

  • Zhu-Jun Wu

  • Hui Gong

  • Ya-Xin Li

  • Yuan Li

  • Wei-Yi Wu

  • Lin-Jie Guo

  • February 6, 2026

  • 0 min

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Objective:

To investigate the endoscopic features of anal and anorectal tumors specifically missed during colonoscopy and provide insights for clinicians.

Key Findings:
  • Approximately 12% of anal and anorectal tumors were missed during endoscopic assessments, highlighting a critical gap in detection.
  • Inadequate visualization and low rates of retroflexion examination significantly contributed to missed diagnoses.
  • Endoscopists' unfamiliarity with tumor features and false-negative biopsy results were identified as major contributing factors.
Interpretation:

Standardizing endoscopic procedures and enhancing endoscopists' knowledge of anal and anorectal tumors through targeted training may significantly reduce missed diagnoses.

Limitations:
  • The retrospective design may introduce selection bias, potentially affecting the reliability of the findings.
  • The study's limitation to a single institution may restrict the generalizability of the results to broader clinical settings.
Conclusion:

Improving detection strategies and comprehensive training for endoscopists is essential to reduce the incidence of missed anal and anorectal tumors, ultimately enhancing patient care.

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