Rare Case report and Literature Review of Peripheral T-Cell Lymphoma Presenting as Massive Gastrointestinal Hemorrhage: An Unusual Etiology Demanding Emergency Surgical Intervention - Summary - MDSpire

Rare Case report and Literature Review of Peripheral T-Cell Lymphoma Presenting as Massive Gastrointestinal Hemorrhage: An Unusual Etiology Demanding Emergency Surgical Intervention

  • By

  • Liu, Zhou

  • Zhang, Liang

  • Chen, Qianqian

  • He, Hua hui

  • Peng, Wei

  • Liu, Yanliang

  • Li, Guang

  • Zhan, Ying li

  • April 20, 2026

  • 0 min

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Objective:

To present a case of peripheral T-cell lymphoma (PTCL) that manifested as severe gastrointestinal bleeding, initially misdiagnosed, and to emphasize the need for urgent surgical intervention.

Key Findings:
  • The patient experienced severe gastrointestinal bleeding due to PTCL, initially misdiagnosed as inflammatory bowel disease.
  • Conservative treatments were ineffective, leading to critical deterioration and the need for surgical intervention.
  • Histopathological analysis confirmed the diagnosis of PTCL post-surgery.
Interpretation:

This case underscores the importance of recognizing PTCL as a potential cause of gastrointestinal bleeding to prevent misdiagnosis and ensure timely surgical intervention.

Limitations:
  • The case study is based on a single patient, limiting generalizability.
  • Potential biases in diagnosis and treatment approaches may exist.
  • The rarity of PTCL may affect the applicability of findings.
Conclusion:

Increased clinical vigilance for PTCL in patients with unexplained gastrointestinal bleeding is crucial for timely diagnosis and intervention.

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