To provide an updated overview of randomised controlled trials (RCTs) related to chronic subdural haematoma (CSDH) and inform clinical practice and future research directions, covering studies published up to February 18, 2025.
Key Findings:
Identified 95 trials (41 published, 54 ongoing) relevant to CSDH management, highlighting a significant increase in research activity.
Recent trials have influenced clinical practice, notably reducing the use of steroids in CSDH treatment, which is now reflected in updated clinical guidelines.
Emerging focus on alternative pharmacological agents and minimally invasive techniques, indicating a shift in treatment paradigms.
Interpretation:
The review highlights the evolving landscape of CSDH treatment and underscores the need for continued high-quality research to establish optimal management strategies, particularly in light of recent findings.
Limitations:
Limited evidence supporting optimal treatment strategies for CSDH, which may lead to inconsistent clinical practices.
Variability in surgical techniques and practices across different regions, potentially affecting patient outcomes.
Conclusion:
This systematic update serves to inform clinicians and researchers about current evidence in CSDH management and identifies areas for future research.
In this procedural case review, vascular surgeon Dr. Samuel Steerman and neurosurgeon Dr. Shannon Clark collaborate to perform an anterior lumbar interbody fusion (ALIF).
