Clinicians should consider CLAPO syndrome in patients with lower lip capillary malformation, especially if accompanied by enlarged venous vessels on the tongue.
Limitations:
The sample size is small due to the low incidence of the disease.
Further studies are needed to clarify pathogenesis, therapeutic efficacy, and genetic characteristics.
Conclusion:
Lower lip capillary malformation is a key feature of CLAPO syndrome, and clinicians should be vigilant in diagnosing this condition.
