To examine the indirect pathway involving depressive symptoms in the association between postoperative sleep duration and postoperative delirium (POD), highlighting its significance for perioperative care.
Key Findings:
Postoperative sleep duration significantly associated with POD (total β=-0.174, direct β=-0.045, 95% CI provided).
Depressive symptoms showed a significant indirect pathway in the relationship between sleep duration and POD (β=-0.129, 95% CI provided).
Significant associations were found for sleep duration impacting depressive symptoms (β=-2.660, 95% CI provided) and depressive symptoms impacting POD (β=0.049, 95% CI provided).
Interpretation:
Depressive symptoms mediate the relationship between sleep duration and POD, indicating the importance of managing both factors in perioperative care, potentially through targeted interventions.
Limitations:
Study limited to patients undergoing specific surgical procedures, which may affect generalizability to other populations.
Potential confounding factors not fully explored or controlled, which may influence the observed associations.
Conclusion:
Concurrent assessment and management of sleep and depressive symptoms are essential for optimizing perioperative care, and future research should explore broader applications of these findings.
