Assessment of Anterior Scleral Thickness in Acromegaly: A Prospective Multinational Optical Coherence Tomography Study - Summary - MDSpire
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Assessment of Anterior Scleral Thickness in Acromegaly: A Prospective Multinational Optical Coherence Tomography Study

  • By

  • Başak Memis

  • Murat Kasikci

  • Gulhan Akbaba

  • Ozgur Erogul

  • February 12, 2026

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Objective:

To systematically assess anterior scleral thickness in patients with acromegaly using high-resolution anterior segment optical coherence tomography (AS-OCT), highlighting its significance for ocular health.

Key Findings:
  • Significant differences in anterior scleral thickness were observed between acromegaly patients and healthy controls (specific statistical results could be added).
  • The study provided insights into the potential impact of acromegaly on ocular biomechanics.
Interpretation:

The findings suggest that acromegaly may lead to scleral thickening, which could influence glaucoma susceptibility and surgical outcomes, emphasizing the need for clinical awareness.

Limitations:
  • The study's sample size, while adequate, may limit the generalizability of the findings, and potential biases or confounding factors should be acknowledged.
  • Measurements from fellow eyes were not statistically independent, which could affect the analysis.
Conclusion:

This study highlights the need for further research on scleral changes in acromegaly and their implications for ocular health, particularly in understanding glaucoma risk.

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