Performance and clinical applicability of machine learning in liver computed tomography imaging: a systematic review - Summary - MDSpire

Performance and clinical applicability of machine learning in liver computed tomography imaging: a systematic review

  • By

  • Keyur Radiya

  • Henrik Lykke Joakimsen

  • Karl Øyvind Mikalsen

  • Eirik Kjus Aahlin

  • Rolv-Ole Lindsetmo

  • Kim Erlend Mortensen

  • May 12, 2023

  • 0 min

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Objective:

To evaluate the application, performance, and clinical relevance of machine learning (ML) in liver computed tomography (CT) imaging through a systematic review.

Key Findings:
  • 191 studies were included, categorized into five groups based on study aims.
  • Liver segmentation was the primary aim in 84 studies, with significant contributions from deep learning methods, highlighting advancements in accuracy and efficiency.
  • Lesion segmentation was a focus in 60 studies, with models performing well on larger lesions but struggling with smaller ones, indicating a need for further development.
Interpretation:

ML shows promising potential in liver CT imaging, particularly in segmentation tasks, but challenges remain in accurately segmenting smaller lesions, suggesting areas for future research.

Limitations:
  • Only 11 out of 87 studies reported results with confidence intervals or standard errors, limiting the robustness of findings.
  • Many studies relied on publicly available datasets, which may limit the diversity and applicability of training data.
Conclusion:

ML applications in liver CT imaging are advancing, but further improvements in model validation and reporting transparency are needed for clinical adoption, emphasizing the importance of rigorous evaluation.

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