Use of WeChat-based patient-doctor interaction improves patient experience of Helicobacter pylori treatment: a randomized controlled trial - Summary - MDSpire

Use of WeChat-based patient-doctor interaction improves patient experience of Helicobacter pylori treatment: a randomized controlled trial

  • By

  • Boshen Lin

  • Wenlin Zhang

  • Jinghui Zhang

  • Minjuan Lin

  • Jing Liu

  • Zhongxue Han

  • Yuming Ding

  • Qingzhou Kong

  • Miao Duan

  • Yueyue Li

  • Xiuli Zuo

  • Yanqing Li

  • May 29, 2026

  • 0 min

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Objective:

To evaluate whether a WeChat-based patient-doctor interaction (WPDI) system could improve H. pylori treatment outcomes and enhance patient experience during treatment.

Key Findings:
  • WPDI group achieved eradication rates of 90.4%, 93.4%, and 94.2% in intention-to-treat, modified intention-to-treat, and per-protocol analyses, respectively.
  • Control group eradication rates were 89.5%, 93.3%, and 94.6% for the same analyses.
  • 90.3% of WPDI patients rated their treatment as satisfactory or very satisfactory compared to 74.9% in the control group (P < 0.001).
  • WPDI patients reported lower levels of worry (16.0% vs. 26.1%; P = 0.012) and perturbation (11.7% vs. 22.7%; P = 0.003) during treatment.
Interpretation:

The WeChat-based patient-doctor interaction significantly improved patient experience during H. pylori eradication therapy, although it did not significantly enhance treatment outcomes.

Limitations:
  • The study was conducted at a single center, which may limit generalizability.
  • The reliance on self-reported measures for patient experience may introduce bias.
  • Cultural factors may affect the generalizability of the findings.
Conclusion:

The WeChat-based patient-doctor interaction improved patient experience significantly during H. pylori eradication therapy.

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