Triglyceride profiles in preterm infants reveal dynamic and age-specific trajectories - Summary - MDSpire

Triglyceride profiles in preterm infants reveal dynamic and age-specific trajectories

  • By

  • Emma R. Gertel

  • Victoria Y. Ding

  • Thanaphong Phongpreecha

  • Feng Xie

  • Andrew Parsons

  • Ivana Marić

  • Nima Aghaeepour

  • Karl G. Sylvester

  • Valerie Y. Chock

  • John A. Kerner

  • Camilia R. Martin

  • David K. Stevenson

  • Gary M. Shaw

  • Jonathan D. Reiss

  • June 12, 2026

  • 0 min

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Objective:

To define triglyceride (TG) values and their associations with gestational age (GA), birth weight (BW), lipid dosing, and postnatal age in preterm infants born <32 weeks.

Key Findings:
  • TG distributions differed significantly by GA, with the highest values in infants born at 22–25 weeks' gestation.
  • In the LPCH cohort, TG levels peaked at approximately two weeks of postnatal age and then declined.
  • Lipid emulsion dosing <2 g/kg/day was associated with a reduced risk of hypertriglyceridemia.
  • Continuous TG values were not consistently associated with major neonatal outcomes such as RDS, BPD, NEC, or ROP.
Interpretation:

Limitations:
  • The study is retrospective and may be subject to biases inherent in observational studies.
  • The association between TG levels and neonatal morbidities was limited.
Conclusion:

Original Source(s)

Triglyceride profiles in preterm infants reveal dynamic and age-specific trajectories

  • by Emma R. Gertel, Victoria Y. Ding, Thanaphong Phongpreecha, Feng Xie, Andrew Parsons, Ivana Marić, Nima Aghaeepour, Karl G. Sylvester, Valerie Y. Chock, John A. Kerner, Camilia R. Martin, David K. Stevenson, Gary M. Shaw, Jonathan D. Reiss

  • June 12, 2026

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