Therapeutic progress in rosacea: targeting the neuro-vascular-immune triad - Summary - MDSpire

Therapeutic progress in rosacea: targeting the neuro-vascular-immune triad

  • By

  • Xingyin Yang

  • Wanqing Yang

  • Nuoran Chen

  • Dansheng Li

  • Yang Xu

  • June 22, 2026

  • 0 min

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Objective:

To summarize the latest advancements in rosacea treatments targeting the neuro-vascular-immune triad.

Approach:
    Key Findings:
    • Abnormal activation of the neuro-vascular-immune triad is a key pathological mechanism in rosacea.
    • Emerging therapies targeting this triad lack large-scale randomized controlled trials.
    • Optimal dosing regimens and treatment durations for these therapies remain unclear.
    Interpretation:

    Future studies should focus on strengthening basic investigations, exploring combined therapeutic strategies, and developing personalized approaches for effective long-term control of rosacea.

    Limitations:
    • Lack of large-scale randomized controlled trials for the discussed therapies.
    • Uncertainty regarding optimal dosing regimens and treatment durations.
    Conclusion:

    This review highlights the need for further research to enhance treatment efficacy and personalization in rosacea management.

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