Reference values and Z-scores for left ventricular global longitudinal strain in healthy Colombian children: an echocardiographic study - Summary - MDSpire
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Reference values and Z-scores for left ventricular global longitudinal strain in healthy Colombian children: an echocardiographic study
To establish GLS reference values in a cohort of healthy children from Colombia and assess age-related differences in GLS.
Key Findings:
GLS varied significantly by age, with more negative values in younger children and progressively less negative values in adolescents, indicating the need for age-specific reference values.
A moderate correlation was found between GLS and age (r = 0.49; p < 0.001), suggesting that age should be considered when interpreting GLS.
Left ventricular ejection fraction remained normal across all age groups, reinforcing the reliability of GLS as a measure of myocardial function.
Interpretation:
The study provides population-specific GLS reference values for healthy Colombian children, emphasizing the importance of age in interpreting GLS and its potential implications for pediatric cardiac assessments.
Limitations:
The study is limited to a single center in Colombia, which may affect generalizability to other populations.
Exclusion criteria may limit the diversity of the sample, potentially impacting the applicability of the findings.
Conclusion:
GLS in this population shows significant variation with age, highlighting the need for age-specific reference values.
