Risk association and diagnostic value of body roundness index for cardiovascular-kidney-metabolic-related outcomes: a systematic review and meta-analysis - Summary - MDSpire
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Risk association and diagnostic value of body roundness index for cardiovascular-kidney-metabolic-related outcomes: a systematic review and meta-analysis
To synthesize evidence on the associations between Body Roundness Index (BRI) and Cardiovascular-Kidney-Metabolic (CKM) outcomes, and to assess BRI's diagnostic performance for metabolic risk factors, ensuring clarity in terminology.
Key Findings:
BRI is significantly associated with multiple CKM-related outcomes, with variations by outcome and gender, based on 93 studies.
Consistent risk associations for metabolic syndrome were observed across the overall population and gender subgroups.
BRI demonstrated good discriminatory ability for metabolic syndrome but limited predictive ability for chronic kidney disease, cardiovascular disease, and mortality.
Interpretation:
BRI shows promise as a complementary tool to conventional indices for identifying and stratifying CKM-related risks, particularly for metabolic abnormalities, without suggesting it replaces them.
Limitations:
The predictive ability of BRI for certain CKM outcomes is constrained.
Further research is needed to define the long-term predictive value and clinical utility of BRI across diverse populations, considering potential biases in the studies reviewed.
Conclusion:
BRI is associated with CKM-related outcomes and offers favorable risk assessment capabilities, warranting further investigation through high-quality prospective studies to solidify its clinical utility.
