Objective:

To synthesize current evidence regarding the clinical utility of ultra-widefield optical coherence tomography angiography (UWF-OCTA) in diabetic retinopathy (DR), with a focus on its ability to identify and characterize key retinal microvascular lesions.

Approach:

Key Findings:

• UWF-OCTA detects neovascularization with high sensitivity and specificity.
• UWF-OCTA offers unique advantages over FA, including non-invasive imaging and depth-resolved information.
• UWF-OCTA compares favorably to UWF-FA in detecting NV.
• Limitations of UWF-OCTA include segmentation errors and a smaller field of view compared to FA.

Interpretation:

UWF-OCTA is a promising non-invasive tool for diagnosing and monitoring diabetic retinopathy, potentially complementing conventional angiography.

Limitations:

• Segmentation errors in imaging.
• Smaller field of view compared to traditional FA.

Conclusion:

UWF-OCTA enhances the ability to visualize peripheral retinal lesions in diabetic retinopathy.

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