Lingering SARS-CoV-2 in Gastric and Gallbladder Tissues of Patients with Previous COVID-19 Infection Undergoing Bariatric Surgery - Summary - MDSpire

Lingering SARS-CoV-2 in Gastric and Gallbladder Tissues of Patients with Previous COVID-19 Infection Undergoing Bariatric Surgery

  • By

  • Mohamed Hany

  • Ahmed Zidan

  • Muhammad Gaballa

  • Mohamed Ibrahim

  • Ann Samy Shafiq Agayby

  • Anwar Ashraf Abouelnasr

  • Eman Sheta

  • Bart Torensma

  • November 1, 2022

  • 0 min

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Objective:

To determine the presence of SARS-CoV-2 nucleocapsid proteins in gastric and gallbladder tissues of patients with a history of COVID-19, particularly those with negative PCR results.

Key Findings:
  • Presence of SARS-CoV-2 nucleocapsid proteins was detected in gastric and gallbladder tissues of some patients, raising concerns about surgical safety.
  • Patients had a history of gastrointestinal symptoms related to COVID-19.
  • Negative PCR results at the time of surgery did not rule out the presence of viral antigens in tissues.
Interpretation:

The findings suggest that SARS-CoV-2 may persist in gastrointestinal tissues despite negative PCR results, raising concerns about the safety of bariatric surgeries in previously infected patients.

Limitations:
  • Small sample size may limit the generalizability of the findings.
  • The study only included patients with a specific history of COVID-19 and gastrointestinal symptoms, which may introduce selection bias.
Conclusion:

Lingering SARS-CoV-2 in gastric and gallbladder tissues poses potential risks during bariatric surgery, necessitating further research to understand the implications for surgical safety.

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