To report a case of appendiceal micronodular PEComa and discuss its clinicopathologic characteristics, emphasizing its significance in the context of existing literature.
Key Findings:
Micronodular PEComa is an extremely rare mesenchymal neoplasm of the appendix with implications for differential diagnosis.
The tumor exhibited abundant eosinophilic granular cytoplasm and small, round nuclei without significant pleomorphism, highlighting its unique histological features.
The patient showed marked improvement of abdominal pain at the latest follow-up, with no evidence of recurrence, suggesting effective surgical intervention.
Interpretation:
This case adds to the limited literature on appendiceal micronodular PEComa, highlighting its subtle histologic features and potential for misdiagnosis.
Limitations:
Only isolated cases of appendiceal micronodular PEComa have been reported, limiting understanding of its pathogenesis and clinical course. Future research should focus on larger case series.
Conclusion:
Further accumulation of cases is necessary to elucidate the pathogenesis, molecular profile, and long-term clinical course of micronodular PEComa, which may inform clinical practice.
