High-Dose Vitamin D 3 Supplementation During Pregnancy and Test-Based Cognitive Performance at Age 10 Years: A - Summary - MDSpire

High-Dose Vitamin D 3 Supplementation During Pregnancy and Test-Based Cognitive Performance at Age 10 Years: A

  • By

  • Olivia Frigast Frederiksen

  • Jens Richardt Møllegaard Jepsen

  • Nicklas Brustad

  • Rebecca Vinding

  • Julie Bøjstrup Rosenberg

  • Parisa Mohammadzadeh

  • María Hernández-Lorca

  • Ann-Marie Malby Schoos

  • Nilo Vahman

  • Birte Y. Glenthøj

  • Birgitte Fagerlund

  • Niels Bilenberg

  • Klaus Bønnelykke

  • Bjørn H. Ebdrup

  • Kristina Aagaard

  • Bo Chawes

  • May 18, 2026

  • 0 min

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Objective:

To investigate the association of high-dose vitamin D3 supplementation during pregnancy with cognitive performance in offspring evaluated at age 10, highlighting its significance in the context of prenatal health.

Key Findings:
  • High-dose vitamin D3 supplementation during pregnancy may have a positive association with cognitive performance at age 10, which contrasts with previous studies showing inconsistent results regarding prenatal vitamin D and cognitive outcomes.
Interpretation:

The findings suggest that adequate vitamin D levels during pregnancy could be crucial for optimal cognitive development in children, potentially influencing clinical practices regarding prenatal care.

Limitations:
  • The original trial was not designed to assess cognitive outcomes, which may affect the robustness of findings, and potential confounding factors, such as [insert specific confounding factors], were not controlled for in the analysis.
Conclusion:

High-dose vitamin D3 supplementation during pregnancy may positively influence cognitive performance in children, warranting further research into specific cognitive domains and long-term outcomes.

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