Rest-activity rhythmicity as digital biomarkers of postoperative recovery and complications in children - Summary - MDSpire

Rest-activity rhythmicity as digital biomarkers of postoperative recovery and complications in children

  • By

  • Michela Carter

  • Rui Hua

  • Megan K. O’Brien

  • Hangil Lee

  • J. Benjamin Pitt

  • Soyang Kwon

  • Renee C. B. Manworren

  • Austin Chen

  • Arianna Edobor

  • Jane Holl

  • Arun Jayaraman

  • Hassan MK Ghomrawi

  • Fizan Abdullah

  • July 2, 2026

  • 0 min

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Objective:

To characterize normative rest-activity rhythmicity (RAR) trajectories related to activity and heart rate in pediatric patients post-appendectomy and compare these trajectories for patients who experienced complications.

Approach:
  • Study Design: Utilized wearable Fitbit devices to collect physical activity and heart rate data from children aged 3-18 who underwent laparoscopic appendectomy for complicated appendicitis.
  • Data Collection: Data were collected from postoperative days 1 to 21, with clinical information extracted from electronic health records and follow-up surveys conducted on specified days.
Key Findings:
  • Rest-activity rhythmicity (RAR) metrics derived from wearable data may serve as biomarkers for postoperative recovery and complications.
  • RAR metrics were able to predict complications up to three days before clinical diagnosis with 91% sensitivity.
Interpretation:

Wearable-derived RAR metrics can provide insights into postoperative recovery trajectories and help identify complications in pediatric patients.

Limitations:
  • The study was limited to children undergoing laparoscopic appendectomy, which may not generalize to other surgical populations.
  • Exclusion of non-English or non-Spanish speaking patients due to translation service constraints.
Conclusion:

Wearable technology may enhance monitoring of postoperative recovery and early detection of complications in pediatric surgical patients.

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