Treatment of brain abscess rupturing into ventricle: a case report and literature review
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By
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Xiaolin Zhang
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Xia Yang
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Junan Hu
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Wenjing Zhang
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Wei Shen
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June 5, 2026
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Objective:
To report a case of brain abscess rupture leading to ventriculitis and review existing literature.
Key Findings:
- The incidence of brain abscess rupture into ventricles is 0.3%–35.0%, with a mortality rate of 84.0%–100.0%.
- Metagenomic next-generation sequencing is effective for identifying pathogens in brain abscess cases.
Interpretation:
The case highlights the importance of early diagnosis and comprehensive treatment strategies in managing brain abscess complications.
Limitations:
- The study is based on a single case report, limiting generalizability.
Conclusion:
Timely intervention and appropriate antibiotic therapy can lead to recovery in patients with brain abscess complicated by ventriculitis.
