To synthesize evidence on the role of viral and fungal infections in nonresolving acute respiratory distress syndrome (ARDS).
Key Findings:
Invasive pulmonary aspergillosis is common in ARDS secondary to severe viral pneumonia, with mortality rates exceeding 50%, highlighting the severity of this complication.
Interpretation:
The interplay between viral and fungal infections in ARDS underscores the urgent need for improved diagnostic and treatment strategies to effectively manage these complications.
Limitations:
Biases in observational studies and limited sample sizes in clinical trials may affect the reliability of the findings.
Conclusion:
Systematic assessment of viral reactivation in ARDS patients may be warranted, given the potential for significant clinical impact despite uncertainties in treatment efficacy.
βAnd when one of these measles cases ends up in a low-immunization community, that's when the ember really has a chance to expand and become a wildfire.β