CLINICOPATHOLOGICAL FEATURES OF ADULT LYMPHOBLASTIC LYMPHOMA: A RETROSPECTIVE MULTICENTER STUDY FROM TÜRKİYE - Summary - MDSpire

CLINICOPATHOLOGICAL FEATURES OF ADULT LYMPHOBLASTIC LYMPHOMA: A RETROSPECTIVE MULTICENTER STUDY FROM TÜRKİYE

  • By

  • Selim, Cem

  • Ciftciler, Rafiye

  • Goren, Deniz

  • Fidan, Kemal

  • ünal, ali

  • Afacan Öztürk, hacer berna

  • albayrak, murat

  • uluköylü mengüç, meral

  • Atagündüz, ışık

  • işleyen, emel

  • özet, gülsüm

  • birtaş ateşoğlu, elif

  • May 6, 2026

  • 0 min

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Objective:

To analyze the clinical data and outcomes of adult patients diagnosed with lymphoblastic lymphoma (LBL) in Turkey.

Key Findings:
  • Median overall survival (OS) for the cohort was 23 months.
  • No significant difference in OS between T-LBL and B-LBL patients (p>0.05).
  • Median progression-free survival (PFS) was 6 months.
  • 5-year OS rate was 6%, indicating the aggressive nature of adult LBL.
  • Associations found between poor outcomes and factors like increased LDH levels, CNS involvement, multi-site disease, cervical lymphadenopathy, failed remission, and male gender.
Interpretation:

The study highlights the aggressive nature of adult LBL and identifies potential clinical characteristics associated with worse survival outcomes.

Limitations:
  • Limited sample size.
  • Dependence on univariate analyses which may not account for confounding factors.
Conclusion:

Findings suggest that specific clinical characteristics may influence survival in adult LBL, warranting further investigation.

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