Tourniquet effect on rocuronium use during lower extremity fracture fixation - Summary - MDSpire

Tourniquet effect on rocuronium use during lower extremity fracture fixation

  • By

  • Madeline M. Lyons

  • Carlo Eikani

  • Robert Burnham

  • Adam Schiff

  • Michael Ander

  • Ashley E. Levack

  • Joseph Cohen

  • February 20, 2026

  • 0 min

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Objective:

To examine the effect of tourniquet use on the duration of rocuronium during fracture fixation of the ankle and hindfoot, addressing a significant knowledge gap.

Key Findings:
  • Average time to regain at least one twitch in the facial nerve was 34.5 minutes, indicating a potential delay in recovery.
  • 76% of patients recovered 3 or more twitches in the facial nerve before any twitches were recorded in the operative extremity, suggesting a discrepancy in monitoring.
  • 19 patients had 2 or fewer twitches at the extremity during tourniquet inflation, highlighting the impact of tourniquet use.
Interpretation:

The study suggests that monitoring twitches at the facial nerve may not accurately reflect the depth of paralysis in the lower extremity when a tourniquet is inflated, which has important implications for anesthesia practice.

Limitations:
  • Small sample size of 25 patients may limit generalizability.
  • Exclusion of patients due to protocol adherence issues or equipment malfunction could introduce bias.
Conclusion:

Tourniquet application significantly affects the monitoring of neuromuscular blockade, indicating that facial nerve twitches may not be reliable for assessing paralysis in the presence of a tourniquet, which is crucial for clinical decision-making.

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