Toward personalized medicine for mal de débarquement syndrome - Summary - MDSpire

Toward personalized medicine for mal de débarquement syndrome

  • By

  • Jun Maruta

  • Catherine Cho

  • Sergei B. Yakushin

  • June 22, 2026

  • 0 min

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Objective:

To examine individual variations in symptom emphasis and their influence on treatment responsiveness in Mal de Débarquement Syndrome (MdDS).

Approach:
    Key Findings:
    • Many symptoms correlated with the overall severity rating, but even those that showed strong correlation among many subjects, such as dizziness, fatigue, and brain fog, were endorsed variably across subjects.
    • A moderate unfavorable dependence on visual sensitivity was found for the responsiveness to the velocity storage attenuation treatment, which distinguished the two treatment approaches.
    Interpretation:

    Individual variations in symptom presentation may influence the choice of treatment approach for MdDS.

    Limitations:
    • The subjective nature of symptom assessment complicates the evaluation of treatment efficacy.
    • Variability in symptom emphasis among patients may affect the generalizability of findings.
    Conclusion:

    Understanding individual symptom emphasis may aid in personalizing treatment approaches for MdDS.

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