Validation and implementation of ambulatory obstructive sleep apnea polygraphy screening combined with wearable semi-continuous heart rhythm monitoring in patients with atrial fibrillation: a validation and a pilot study - Summary - MDSpire
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Validation and implementation of ambulatory obstructive sleep apnea polygraphy screening combined with wearable semi-continuous heart rhythm monitoring in patients with atrial fibrillation: a validation and a pilot study
To validate the NOX-T3s polygraphy device for OSA screening and evaluate the feasibility of a structured OSA screening pathway combined with semi-continuous heart rhythm monitoring in AF patients.
Approach:
Validation Study: Evaluated NOX-T3s performance in 30 AF patients undergoing PSG with simultaneous and consecutive home recordings.
Pilot Study: Used NOX-T3s for ambulatory OSA screening in another 30 AF patients, followed by 31 days of semi-continuous rhythm monitoring via a smartwatch.
Key Findings:
NOX-T3s showed good diagnostic performance for detecting moderate-to-severe OSA (AUC 0.83 simultaneous; 0.80 home).
An optimized AHI cut-off of 11.1 events/h improved accuracy (0.85) with high sensitivity (92.9%) and specificity (75.0%).
OSA screening was successful in 97.1% of patients, identifying moderate-to-severe OSA in 79.3%.
Semi-continuous rhythm monitoring was successful in 96.6%, detecting AF in 64.3% of patients.
Interpretation:
NOX-T3s with an AHI cut-off ≥11.1 events/h is a home screening tool for moderate-to-severe OSA, and its combination with rhythm monitoring is feasible in AF patients.
Conclusion:
The study supports the use of NOX-T3s for OSA screening in AF patients.
