Surgical management and functional outcomes of cranial infections requiring craniotomy or craniectomy: a retrospective cohort study - Summary - MDSpire

Surgical management and functional outcomes of cranial infections requiring craniotomy or craniectomy: a retrospective cohort study

  • By

  • Daniel W. Griepp

  • Shivum Desai

  • Heather Heitkotter

  • Rabia Ahmed

  • Avery Roe

  • Bryce K. Sarcar

  • Ishan Perera

  • Joshua Caskey

  • Jeffrey P. Turnbull

  • Julio Rosado Philippi

  • Elise J. Yoon

  • Ammar Alsalahi

  • James Dragonette

  • Anna T. K. Griepp

  • Clifford M. Houseman

  • Prashant Kelkar

  • Chad F. Claus

  • Boyd F. Richards

  • Daniel A. Carr

  • June 22, 2026

  • 0 min

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Objective:

To describe the institutional experience with the surgical management of non-catheter-related cranial infections requiring craniotomy or craniectomy, including patient characteristics, microbiology, perioperative practices, and functional outcomes.

Approach:
    Key Findings:
    • Poor outcomes (mRS 4–6 or ≥3 revision surgeries) occurred in 13 patients (34.2%) and were associated with higher Charlson Comorbidity Index (p < 0.02) and underlying high-grade glioma or metastatic disease (p = 0.04).
    Interpretation:

    Limitations:
    • The sample size is relatively small, which may limit the generalizability of the findings.
    Conclusion:

    This institutional series highlights the complexities of managing cranial infections and the impact of pre-existing conditions on outcomes.

Original Source(s)

Surgical management and functional outcomes of cranial infections requiring craniotomy or craniectomy: a retrospective cohort study

  • by Daniel W. Griepp, Shivum Desai, Heather Heitkotter, Rabia Ahmed, Avery Roe, Bryce K. Sarcar, Ishan Perera, Joshua Caskey, Jeffrey P. Turnbull, Julio Rosado Philippi, Elise J. Yoon, Ammar Alsalahi, James Dragonette, Anna T. K. Griepp, Clifford M. Houseman, Prashant Kelkar, Chad F. Claus, Boyd F. Richards, Daniel A. Carr

  • June 22, 2026

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