To report a case of persistent Mpox infection with prolonged PCR positivity lasting over one year in a patient with advanced HIV, highlighting its clinical significance.
Key Findings:
The patient had Mpox PCR positivity for over one year.
Initial treatment with tecovirimat did not completely resolve lesions, indicating treatment challenges in immunocompromised patients.
Multiple PCR tests remained positive during hospitalization.
Interpretation:
This case highlights the potential for prolonged Mpox infection and PCR positivity in immunocompromised patients, particularly those with advanced HIV, suggesting a need for tailored management strategies.
Limitations:
Single case report limits generalizability, particularly in diverse patient populations.
Lack of long-term follow-up data post-discharge may obscure understanding of Mpox persistence.
Conclusion:
The findings suggest that Mpox may persist longer in immunocompromised individuals, necessitating careful monitoring and management, and underscore the need for further research in this area.
