OPTIONS-DC: Treatment Course Outcomes Following Outpatient Parenteral Antimicrobial Therapy RN–Led Multidisciplinary Care Conferences for People Who Use Drugs Hospitalized With Complex Infections - Summary - MDSpire

OPTIONS-DC: Treatment Course Outcomes Following Outpatient Parenteral Antimicrobial Therapy RN–Led Multidisciplinary Care Conferences for People Who Use Drugs Hospitalized With Complex Infections

  • By

  • Alyse H Douglass

  • Heather Mayer

  • Kathleen Young

  • Amber C Streifel

  • Heather Franklin

  • Jina T Makadia

  • Liz Parkes-Perret

  • Luke C Strnad

  • Monica K Sikka

  • February 28, 2025

  • 0 min

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Objective:

To evaluate treatment outcomes associated with the OPTIONS-DC multidisciplinary care conference for patients with substance use disorders requiring long-term intravenous antimicrobials.

Key Findings:
  • 75.1% of patients completed their antimicrobial course.
  • Median age of participants was 38 years, with 93.5% having active substance use.
  • Having a primary care provider at the time of conference was associated with higher treatment completion rates (odds ratio 4.50).
Interpretation:

The OPTIONS-DC conference is associated with high rates of antimicrobial course completion and supports the integration of harm reduction principles in discharge planning for patients with substance use disorders.

Limitations:
  • Retrospective nature of treatment outcome data collection.
  • Potential biases in patient selection and reporting.
Conclusion:

The OPTIONS-DC model demonstrates effective discharge planning and treatment adherence for patients with complex infections and substance use disorders, highlighting the importance of multidisciplinary approaches.

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