Prevalence and Regional Differences of Diabetic Retinopathy in Sub-Saharan Africa: Insights from a Systematic Review and Meta-Analysis - Summary - MDSpire
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Prevalence and Regional Differences of Diabetic Retinopathy in Sub-Saharan Africa: Insights from a Systematic Review and Meta-Analysis
To predict the pooled prevalence of diabetic retinopathy (DR) in adults with diabetes in Sub-Saharan Africa (SSA) and examine regional variations to inform public health strategies.
Key Findings:
The pooled prevalence of DR in SSA was found to be approximately 36%, with significant regional variations observed.
There was significant heterogeneity in DR prevalence across different regions of SSA, with reported rates ranging from low teens to over 50%.
Factors such as study design, population characteristics, and diagnostic methods contributed to variations in reported prevalence rates.
Interpretation:
The findings highlight a substantial burden of DR among diabetic populations in SSA, emphasizing the need for improved screening and healthcare resources.
Limitations:
Limited number of studies from certain regions may affect the generalizability of results, particularly in underrepresented areas.
Variability in diagnostic methods and study quality could influence prevalence estimates, potentially leading to under- or overestimation.
Conclusion:
This systematic review provides a comprehensive estimate of DR prevalence in SSA, underscoring the urgent need for enhanced diabetic screening and healthcare infrastructure, and highlights areas for future research.
US claims data showed rising prevalence of diabetic retinal disease in type 1 and type 2 diabetes, while incidence declined in type 1 diabetes and moved closer to type 2 rates by 2022.
