Diagnostic value of peroral choledochoscopy combined with modified biopsy forceps for malignant biliary strictures: a two-center retrospective study - Summary - MDSpire

Diagnostic value of peroral choledochoscopy combined with modified biopsy forceps for malignant biliary strictures: a two-center retrospective study

  • By

  • Geqi Zhu

  • Yu Jin

  • Cuihua Qi

  • Shuxin Tian

  • Hao Liu

  • Weigang Chen

  • Rong Lin

  • Guochen Shang

  • June 18, 2026

  • 0 min

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Objective:

To evaluate the diagnostic value and safety of peroral cholangioscopy (POCS) combined with modified biopsy forceps for malignant biliary strictures (MBS).

Approach:
    Key Findings:
    • Biliary strictures can be benign or malignant, with misdiagnosis leading to unnecessary surgical interventions.
    • POCS allows for direct visualization and targeted biopsy, improving diagnostic accuracy for MBS.
    • Modified biopsy forceps were developed to enhance access and sampling capability during POCS.
    Interpretation:

    Limitations:
    • Retrospective design may introduce bias.
    • Single-center studies may limit generalizability.
    Conclusion:

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